Autoimmune and Rare Diseases,  First Aid and Emergency

Gastroparesis: symptoms, triggers, and therapeutic options

Gastroparesis is a condition in which the muscles of the stomach do not function properly, leading to serious digestive problems. Normal stomach function requires strong muscle contractions that help food pass through the digestive system. If these muscles work weakly or do not contract at all, the emptying of the stomach slows down, which can cause various unpleasant symptoms, such as nausea, vomiting, and fluctuations in blood sugar levels.

Gastroparesis complicates the lives of many people, as the improper functioning of the stomach affects not only digestion but also overall well-being. Patients often experience a feeling of fullness after consuming just a few bites, making it difficult to maintain proper nutrition. Additionally, due to the disruption of stomach emptying, various metabolic problems may also arise.

Although gastroparesis is currently not curable, alleviating its symptoms is possible through dietary changes and medications. Experts are continuously working on developing effective treatment methods to improve the quality of life for patients.

The Symptoms of Gastroparesis

The signs and symptoms of gastroparesis encompass a wide range and can significantly impact patients’ daily lives. One of the most common complaints is a feeling of fullness, which can occur after consuming just a few bites. This phenomenon often prevents proper nutrition, leading to patients becoming malnourished.

Blood sugar fluctuations are also a characteristic symptom associated with the slow emptying of the stomach. Since nutrient absorption after meals is not uniform, blood sugar levels can fluctuate, which can be particularly dangerous for diabetics. Patients with gastroparesis often experience weight loss as digestion and nutrient absorption are inadequate.

Furthermore, due to food remaining in the stomach, various complications can arise, such as excessive growth of stomach bacteria. Undigested food may begin to ferment, disrupting the balance of gut flora. In addition to these problems, hardened food in the stomach, known as a bezoar, can also occur, causing nausea and vomiting, and potentially creating life-threatening situations if it prevents food from entering the small intestine.

The Causes of Gastroparesis

Several factors can underlie gastroparesis, but the most common cause is damage to the vagus nerve. This nerve plays a key role in stomach movement, and if it is injured, the stomach muscles do not receive the necessary signals, preventing them from functioning properly.

Common causes include long-term diabetes, which presents as a complication in a significant portion of patients. Additionally, abdominal surgeries, certain medications (such as narcotic pain relievers and antidepressants), and cancer treatments can also contribute to the development of the condition.

Other conditions, such as anorexia, bulimia, scleroderma, Parkinson’s disease, or hypothyroidism, can also trigger symptoms of gastroparesis. Nerve damage can thus lead to a wide range of problems that affect stomach function.

The Diagnosis and Treatment of Gastroparesis

The diagnosis of gastroparesis involves multiple steps and requires various tests. Doctors typically use ultrasound examinations to assess stomach movement and detect any abnormalities. Additionally, the rate of stomach emptying can be measured using food containing radioactive material, which helps determine the effectiveness of stomach function.

Laboratory tests, such as blood and stool samples, are also important for diagnosing the complications and metabolic diseases associated with gastroparesis. After a diagnosis is established, treatment begins with addressing the underlying condition.

Dietary changes play a crucial role in the treatment of gastroparesis. Doctors generally recommend consuming easily digestible foods and suggest cooking or steaming high-fiber vegetables and fruits. Low-fat foods and pureed foods, such as soups, are also recommended as they aid in easier digestion.

Medications include those that treat nausea and vomiting, as well as prokinetics that stimulate the stomach muscles. These medications enhance the movement of the digestive system, facilitating faster passage of food from the stomach to the small intestine. If symptoms worsen, surgical intervention may also be necessary.

In severe cases, when the patient is unable to consume food or drink, artificial nutrition may be required, which is administered via a tube. Therefore, the treatment of gastroparesis requires a complex approach focused on improving the patient’s quality of life.