The Denys-Drash syndrome is a rare but serious genetic condition that can lead to several significant health problems. The disease typically involves kidney dysfunction, childhood kidney tumors, and developmental abnormalities of the genitalia. The underlying cause of these disorders is a mutation in the WT1 gene, which plays a key role in the development of the kidneys and genitalia. The consequences of the syndrome begin in childhood, but the long-term effects can present significant challenges for patients and their families. For children living with Denys-Drash syndrome, the disease is often diagnosed in the early years, when kidney dysfunction becomes apparent. Due to the complexity of the syndrome, it is important…