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Martin-Bell Syndrome: The Weakness of the X Chromosome
The fragile X syndrome, also known as Martin-Bell syndrome, is a hereditary disorder associated with the vulnerability of the X chromosome. This condition is the second most common cause of congenital intellectual disability, following Down syndrome. Among affected individuals, the prevalence of the disorder is more common in boys, but it can also manifest in girls, albeit in a different form. Research has provided a precise understanding of the genetic background of the disorder. A repeating amino acid sequence on the X chromosome typically occurs a maximum of 31 times. However, if this repetition exceeds a critical number, the chromosome becomes unstable, leading to the development of fragile X syndrome.…