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The disease of thalassemia
The hemoglobin, a protein found in red blood cells, plays a crucial role in the body’s oxygen supply. The level and function of hemoglobin are key to ensuring that tissues receive adequate oxygen, as any disruption in hemoglobin formation can lead to anemia and hypoxic conditions. The macromolecules that make up hemoglobin have a complex structure, which includes a heme ring containing iron and four globin chains, two of which are alpha and two are non-alpha isoforms. Among the disorders of hemoglobin formation, thalassemia plays a prominent role, a group of hereditary diseases that affect the globin chain of hemoglobin. This disease complicates the normal production of hemoglobin, leading to…