The use of painkillers is part of many people’s daily routines, whether for headaches, muscle cramps, or other painful conditions. People often believe that over-the-counter medications are safe and have no harmful effects. However, the reality is different: painkillers, which have long been considered sources of relief, actually pose serious health risks. Mechanism of Action of Painkillers The mechanism of action of painkillers is complex, and their long-term use can have detrimental effects on several organs, particularly the kidneys. Kidney failure, which signifies a decline in kidney function, can occur for various reasons, and the use of painkillers is a significant risk factor. This is due to the nephrotoxic effects…