The marble bone disease, also known as osteopetrosis, is an extremely rare and unique genetic condition characterized by the pathological thickening of bones. The essence of the disease is that the mineral content of bone tissue, particularly calcium, significantly increases, causing the bones to appear white like marble on X-rays. The underlying cause of this condition is a decrease in the number or dysfunction of bone-resorbing cells, namely osteoclasts. The appearance and course of this disease have often sparked scientific interest, but descriptions made for the sake of popularization often contain exaggerations. Writings and films about marble bone disease frequently fail to convey the true severity and consequences of the…