-
Parkinson’s Disease: What Does Reduced Drug Efficacy Mean?
A key factor in the treatment of Parkinson’s disease is the effectiveness of medications. However, over time, patients may often experience a decrease in the effectiveness of their medications, a phenomenon known as “wearing off.” This process is particularly noticeable with the use of levodopa, when the duration of the drug’s effect shortens, and symptoms appear earlier than the next dose is due. The wearing off phenomenon affects not only motor symptoms but also non-motor symptoms, which become fluctuating in nature. Research shows that a significant portion of patients treated with levodopa may experience this issue, regardless of how many years they have been on the medication. Therefore, it is…
-
Treatment of Spinal Cord Injury Using mRNA Technology
The treatment of spinal cord injuries presents a significant challenge for science and medicine. The inflammatory processes that occur as a result of the injuries can damage not only the injured area but also the surrounding healthy tissues. Therefore, it is crucial to perform effective interventions as soon as possible. The time factor plays a prominent role in the success of recovery, as delays can further worsen the injured condition. To reduce inflammation and promote regeneration, numerous research efforts are underway worldwide. The Neuroregeneration Laboratory at the University of Szeged, led by Professor Antal Nógrádi, has been working for years on more effective treatments for spinal cord injuries. By applying…
